The Predictive Value of Mesenteric and Cerebral Tissue Oxygenation Measurements for Feeding Intolerance and Necrotizing Enterocolitis in Preterm

Introduction: Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality in preterm infants.Early detection of impaired intestinal perfusion may support preventive strategies.Near-infrared spectroscopy (NIRS) is a non-invasive bedside method that continuously measures regional tissue oxygenation.This study aimed to assess whether baseline regional cerebral oxygen saturation (rcSO 2 ), regional mesenteric/splanchnic oxygen saturation (rsSO 2 ), and their ratio (SCOR), measured within the first 24-48 hours of life, could predict the development of NEC.Methods: This prospective cohort study included preterm infants with gestational age