Letter to the Editor Re: “Preferred Retinal Locus in Juvenile Macular Dystrophy”

making it difficult to distinguish spontaneous adaptation from training effects.3 Third, fixation stability was quantified using maximum dispersion of fixation points rather than standardized metrics such as the bivariate contour ellipse area.This methodological choice may limit comparability with other studies and underestimate subtle instability.4 Fourth, the absence of a control group (e.g., age-matched individuals with other macular diseases) restricts the ability to contextualize whether observed PRL behaviors are unique to JMD or reflect broader adaptation mechanisms.5 Finally, the modest sample size precluded subgroup analyses by disease severity or lesion morphology, which could have provided more nuanced insights into PRL adaptation. 2 Despite these limitations, the study contributes meaningfully to our understanding of PRL behavior in JMD.Future prospective, longitudinal studies with larger, genetically characterized cohorts and standardized fixation metrics will be essential to fully elucidate PRL adaptation and optimize rehabilitation strategies for young patients with central vision loss.