Appearance of necrotizing sialometaplasia temporarily associated with MDMA consumption
Abstract
We reported the case of a 24-year-old woman presented with necrotizing sialometaplasia associated temporally with 3,4-methylenedioxymethamphetamine (MDMA) use. The patient reported having consumed MDMA powder licked onto the oral mucosa days before the appearance of the lesions. Symptomatic treatment of the presenting lesions was carried out, with a follow-up that demonstrated complete healing of the lesions. The clinical case is presented and possible pathophysiological mechanisms that may justify the relationship between MDMA and necrotizing sialometaplasia are discussed. This report describes the relationship between a new, previously undescribed aetiological factor related to necrotizing sialometaplasia.
Fields of Study & Subjects
Forensic Toxicology and Drug Analysis
Facial Rejuvenation and Surgery Techniques
Salivary Gland Tumors Diagnosis and Treatment
Publication details
- Journal / source
- Journal of Clinical and Experimental Dentistry
- Publisher
- Medicina Oral, S.L.
- Volume
- 18
- Issue
- 3
- Pages
- e420–e423
- Publication date
- 1 January 2026
- Language
- EN