Synthesis of DNA on Silica Surfaces

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Authors: Marvin H. Caruthers
Cited by: 0

Abstract

Modern methods for synthesizing DNA involve using silica based supports and deoxynucleoside 3'-phosphor-amidites as synthons. Compounds of any defined sequence and up to 150 nucleotides in size have been prepared using this chemistry.

Fields of Study & Subjects

DNA and Nucleic Acid Chemistry Chemical Synthesis and Analysis Advanced biosensing and bioanalysis techniques

Publication details

Journal / source
CRC Press eBooks
Pages
105–113
Publication date
2 February 2026
Language
EN
Document type
Book chapter