Effect of Aminoglutethimide Alone or Combined with Tamoxifen on the Growth of Breast Cancer Cells

Routledge eBooks 2026 Book chapter

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Authors: G. Sica, Fortunata lacopino, G. Ambroso, FO Ranelletti, della Cuna Gicacchina Robustelli
DOI: 10.4324/9781003760542-34
Cited by: 0

Abstract

CG-5 cells are a variant of the MCF-7 cell line, which was obtained in our laboratory in 1981.These cells are characterized by a pronounced responsiveness to estrogens and contain estrogen, androgen, glucocorticoid and progesterone receptors 1 . CG -5 cells have been used to investigate on the antiproliferative activity of different drugs, mainly acting through receptorial mechanism and currently employed in the therapy of hormone-sensitive breast cancer, such as antiestrogens and progestins 2 , 3 .

Fields of Study & Subjects

Estrogen and related hormone effects Breast Cancer Treatment Studies Advanced Breast Cancer Therapies

Publication details

Journal / source
Routledge eBooks
Pages
165–172
Publication date
30 January 2026
Language
EN
Document type
Book chapter