In Vitro Modification of Cytotoxic Efficacy of Doxoru-Bicin After Estrogenic Pretreatment in MCF-7 Cells.

Routledge eBooks 2026 Book chapter

View at publisher
Authors: Leonessa Fabio, T Coialbu, Romanini Antonella, Toma S.
DOI: 10.4324/9781003760542-4
Cited by: 0

Abstract

Chemosensitivity of estrogen-receptor positive (ER+) cells to antineoplastic agents could be selectively improved by means of an adequate estrogenic pre-treatment 1 , 2 , 3 , through mechanisms probably involving estrogen-induced cell kinetic recruitment 4 and, may be, also other undefined forms of favour rable interaction at the cellular level.Kinetics represent indeed the rational basis for the use of estrogenic agents, preceding chemotherapy of breast cancer, in some clinical trials that have been undertaken during last years 5 , 6 .

Fields of Study & Subjects

Estrogen and related hormone effects Breast Cancer Treatment Studies Bioactive Compounds and Antitumor Agents

Publication details

Journal / source
Routledge eBooks
Pages
15–20
Publication date
30 January 2026
Language
EN
Document type
Book chapter