Expression of K Ras Oncogene in Lung Cancer: Preliminary Results

Routledge eBooks 2026 Book chapter

View at publisher
Authors: Daniela Volpes, Vincenzo Bellia, Aurelio Maggio, Rosalba Di Marzo, Francesco Paolo Caronia, G Bonsignore
DOI: 10.4324/9781003760542-42
Cited by: 0

Abstract

A common abnormality of malignant cells is alteration in g e netic expression: in particular point mutations; area cha racteristic of the ras oncogene family, leading to qualitative alterations of the encoded 21-kda proteins, designated p21 1-8 . Recently a guanine-to-cytosine transversion has been identified as responsible for the acquisition of malignant properties by k-ras genes in lung tumor cell lines, as well as in a squamous cell carcinoma tissue sample 9 .

Fields of Study & Subjects

Protein Kinase Regulation and GTPase Signaling Lung Cancer Treatments and Mutations Lung Cancer Research Studies

Publication details

Journal / source
Routledge eBooks
Pages
215–218
Publication date
30 January 2026
Language
EN
Document type
Book chapter