Selective Screening of Natural Products: A Resource for the Discovery of Novel Antmalarial Compounds

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Authors: Cindy K. Angerhofer, Gabriele M. König, Anthony D. Wright, O. Sticher, Wilbur K. Milhous, Geoffrey A. Cordell, Norman R. Farnsworth, John M. Pezzuto
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Abstract

Malaria continues to be a predominant cause of morbidity and mortality in the world today. Over 40% of the global population lives in areas where malaria is endemic, and the annual incidence of the disease is estimated to be 200 million clinical cases, with over 100 million of these in sub-Saharan Africa alone. 1 , 2 An estimated one to two million of the total annual cases result in death, primarily of infants and children.

Fields of Study & Subjects

Malaria Research and Control Pharmaceutical Quality and Counterfeiting Chemical synthesis and alkaloids

Publication details

Pages
311–329
Publication date
8 January 2026
Language
EN
Document type
Book chapter