Deciphering Teochew population’s genetic protective barrier: Apolipoprotein E- lipoprotein(a) kringle IV type 2 synergy as novel cardioprotective pathway

World Journal of Cardiology 2026 Open access

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Authors: Ru-Tong Wang, Yingqi Feng, Si-Qi Tu, Yang Shen
DOI: 10.4330/wjc.v18.i1.113327
Cited by: 0
References: 6

Abstract

provides crucial regional data for precision cardiovascular medicine in East Asia. This study focuses on the Teochew Han population in China for the first time and reveals the synergistic protective effect of the apolipoprotein E ε2 allele and high copy numbers of kringle IV type 2. This discovery holds significant importance for optimizing regional risk assessment models.

Fields of Study & Subjects

Lipoproteins and Cardiovascular Health Genetic Associations and Epidemiology Paraoxonase enzyme and polymorphisms

Publication details

Journal / source
World Journal of Cardiology
Volume
18
Issue
1
Pages
113327–113327
Publication date
15 January 2026
Language
EN