Ultrasound-based thyroid volume of Cambodian adults

Background:Accurate assessment of thyroid gland size is essential for diagnosing and managing thyroid disorders. While ultrasonography is a non-invasive and cost-effective method for evaluating thyroid volume, no reference values currently exist for the adult Cambodian population. Objective:This study aimed to determine normative ultrasound-based thyroid volume values in euthyroid Cambodian adults, hypothesizing that thyroid volume varies significantly by sex and lobe side. Materials and Methods: A prospective cross-sectional study was conducted on 513 adults (306 females, 207 males) aged 18–78 years at the xxxx between April and November 2020. Inclusion criteria included normal thyroid parenchyma and absence of nodules on ultrasound. Volumes of both lobes were calculated using the ellipsoid formula: Height × Width × Thickness × π/6. Data were analyzed using Excel and SPSS version 26, with significance set at p