Eosinophilic granulomatosis with polyangiitis associated with hepatitis B virus: Diagnostic and therapeutic challenges (a clinical case report)

The present article describes a rare clinical case of eosinophilic granulomatosis with polyangiitis in a 63-year-old patient presenting with polyneuropathy, marked weight loss, and vasculitis rash on the lower extremities. In addition to the primary disease, the patient had a history of active chronic hepatitis B virus infection, drawing attention to a possible association between viral infection and the development of vasculitis. The pathophysiological mechanisms underlying the development of polyneuropathy in this patient are discussed, along with the therapeutic approach involving glucocorticoids and azathioprine, which led to clinical stabilization. The article emphasizes the importance of comprehensive diagnostic evaluation and a differential therapeutic strategy, particularly in the context of coexisting viral hepatitis and autoimmune disease.