Giant Vascular Eccrine Spiradenoma of the Thigh: A Rare Painful Adnexal Tumor in a 40-Year-Old Man

Journal of Pathology Research Reviews & Reports 2026 Open access

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Authors: Essaoudi Mohamed Amine, Mohamed Reda Elochi, El Ktaibi Abderrahim, Allaoui Mohamed, Hafsa Chahdi, Damiri Amal, Oukabli Mohamed
DOI: 10.47363/jpr/2026(8)189
Cited by: 0

Abstract

We report a rare case of a giant vascular eccrine spiradenoma arising in the thigh of a 40-year-old man. The lesion measured 4 cm, was clinically painful, and was evaluated radiologically and histopathologically. The tumour showed the classical biphasic cellular architecture of spiradenoma with prominent vascularized stroma. Immunohistochemistry demonstrated diffuse positivity for pancytokeratin AE1/AE3, strong SMA positivity, and complete negativity for C34. Complete excision resulted in uneventful recovery with no recurrence after 12 months

Fields of Study & Subjects

Cancer and Skin Lesions Soft tissue tumors and treatment Soft tissue tumor case studies

Publication details

Journal / source
Journal of Pathology Research Reviews & Reports
Volume
8
Issue
1
Pages
1–1
Publication date
5 February 2026
Language
EN