Animal Model for Diabetes Co-Existing with Metabolic Syndrome

Animal models have been used extensively in diabetes research.Rat is extensively used as a suitable animal model for understanding the metabolic profile and pathology involved in different stages of type II diabetes.Many animal models have been developed and studied to elucidate molecular mechanisms functional alterations associated with metabolic diseases.Appropriate characterized and clinically relevant experimental models are considered as essential tools for testing new agents, understanding the molecular basis, their pathogenesis and mechanism of actions.In this review, we collate and discuss the various animal models of Diabetes with cardiometabolic complication.The review also be discussed to provide the readers with a comprehensive overview on the selection of the best animal models to meet their research purpose.