Prevalence of p16-positive Squamous Cell Carcinoma of the Oropharynx in a Tertiary Government Hospital in the Philippines

Acta Medica Philippina 2026 Open access

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Authors: Emilio Raymund G. Claudio, Patricia Ann U Soriano, Cesar Vincent Villafuerte, Timothy Carl F Uy, Jose M. Carnate, Andrea R. Villaruel, Anna Kristina Hernandez
DOI: 10.47895/amp.vi0.13060
Cited by: 0
References: 20

Abstract

Objective. This study aimed to determine the hospital-based prevalence of human papilloma virus (HPV)-associated oropharyngeal squamous cell carcinoma (SCC) among patients in a tertiary government institution in the Philippines using immunohistochemical (IHC) staining for p16 as surrogate marker. Methods. This retrospective cross-sectional study included patients with oropharyngeal SCC from January 1, 2015 to December 31, 2021 who had available histopathology tissue blocks. Age, sex, and primary tumor site were extrapolated from charts and p16 status was determined using immunohistochemistry staining. Chi-square test and Fisher’s exact tests were performed for select variables and p16 positivity. A p-value of

Fields of Study & Subjects

Head and Neck Cancer Studies Cervical Cancer and HPV Research Oral Health Pathology and Treatment

Publication details

Journal / source
Acta Medica Philippina
Publication date
1 January 2026
Language
EN