Assessment of left ventricular global longitudinal strain in patients with severe aortic valve stenosis before and after surgery using 2d speckle-tracking echocardiography

Objective: To evaluate changes in left ventricular global longitudinal strain (GLS) in patients with severe aortic valve stenosis before and after surgical aortic valve replacement using two-dimensional speckle-tracking echocardiography. Methods: A prospective, cross-sectional study conducted in patients with severe aortic valve stenosis undergoing surgery, with longitudinal follow-up at 1 month and 3 months postoperatively. The study was carried out at the Cardiovascular Center, E Hospital, from October 2024 to November 2025. Results: A total of 30 patients were included, with a mean age of 64.5 ± 6.0 years, and 56.7% were male. Preoperatively, the mean left ventricular ejection fraction (EF) was 55%, the mean GLS was −15.7 ± 4.8, and the mean transaortic pressure gradient was 54.7 ± 16.5 mmHg. Postoperatively, global longitudinal strain showed a trend toward improvement over the follow-up period at 1 week and 3 months, respectively. Postoperative GLS demonstrated a strong correlation with preoperative EF and left ventricular end-diastolic diameter. Conclusions: Left ventricular global longitudinal strain assessed by 2D speckle-tracking echocardiography is a useful parameter for evaluating left ventricular function in patients with severe aortic valve stenosis before and after surgical valve replacement and shows a strong correlation with conventional echocardiographic parameters.