CMedBench: A Comprehensive Benchmark for Efficient Medical Large Language Models

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Authors: Association for Artificial Intelligence 2026, Yifu Ding, Shengbo Gao, Shenyan Gu, Jinyang Guo, Aishan Liu, Xianglong Liu, Yuqing Ma, Lixian Su, Zhiwang Zhang
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Abstract

Large Language Models (LLMs) hold significant potential for enhancing healthcare applications, yet their deployment is hindered by high computational and memory demands. Model compression techniques, such as quantization and sparsification, offer solutions to reduce these demands, but their impact on medical LLMs remains underexplored. We introduce CMedBench, the first comprehensive benchmark for evaluating compressed LLMs in medical contexts. LLMCMedBench assesses five core dimensions: Medical Knowledge Ability, Medical Application Ability, Trustworthiness Maintenance, Compression Cross Combination, and Computational Efficiency. Through extensive empirical studies, we analyze the trade-offs between model efficiency and clinical performance across diverse models, datasets, and compression strategies. Our findings highlight critical limitations in current evaluation practices and provide a robust framework for aligning compression strategies with medical requirements. CMedBench serves as a vital resource for researchers and practitioners, guiding the development of efficient, trustworthy, and clinically effective LLMs for healthcare applications.

Fields of Study & Subjects

Artificial Intelligence in Healthcare and Education Advanced Neural Network Applications Topic Modeling

Publication details

Journal / source
Underline Science Inc.
Publication date
7 January 2026
Language
EN