MedS³: Towards Medical Slow Thinking with Self-Evolved Soft Dual-sided Process Supervision

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Authors: Association for Artificial Intelligence 2026, Zhe Chen, Shuyang Jiang, Yusheng Liao, Yu Wang, Yanfeng Wang, Ya Zhang, Ya Zhang
Cited by: 0

Abstract

Medical language models face critical barriers to real-world clinical reasoning applications. However, mainstream efforts, which fall short in task coverage, lack fine-grained supervision for intermediate reasoning steps, and rely on proprietary systems, are still far from a versatile, credible and efficient language model for clinical reasoning usage. To this end, we propose MedS$^3$, a self-evolving framework that imparts robust reasoning capabilities to small, deployable models. Starting with 8,000 curated instances sampled via a curriculum strategy across five medical domains and 16 datasets, we use a small base policy model to conduct Monte Carlo Tree Search (MCTS) for constructing rule-verifiable reasoning trajectories. Self-explored reasoning trajectories ranked by node values are used to bootstrap the policy model via reinforcement fine-tuning and preference learning. Moreover, we introduce a soft dual process reward model that incorporates value dynamics: steps that degrade node value are penalized, enabling fine-grained identification of reasoning errors even when the final answer is correct. Experiments on eleven benchmarks show that MedS$^3$ outperforms the previous state-of-the-art medical model by +6.45 accuracy points and surpasses 32B-scale general-purpose reasoning models by +8.57 points. Additional empirical analysis further demonstrates that MedS$^3$ achieves robust and faithful reasoning behavior.

Fields of Study & Subjects

Artificial Intelligence in Healthcare and Education Machine Learning in Healthcare Multimodal Machine Learning Applications

Publication details

Journal / source
Underline Science Inc.
Publication date
7 January 2026
Language
EN