Do We Need Perfect Data? Leveraging Noise for Domain Generalized Segmentation
Abstract
Domain generalization in semantic segmentation faces challenges from domain shifts, particularly under adverse conditions. While diffusion-based data generation methods show promise, they introduce inherent misalignment between generated images and semantic masks. This paper presents FLEX-Seg (FLexible Edge eXploitation for Segmentation), a framework that transforms this limitation into an opportunity for robust learning. FLEX-Seg comprises three key components: (1) Granular Adaptive Prototypes (GAP) that captures boundary characteristics across multiple scales, (2) Uncertainty Boundary Emphasis (UBE) that dynamically adjusts learning emphasis based on prediction entropy, and (3) Hardness-Aware Sampling (HAS) that progressively focuses on challenging examples. By leveraging inherent misalignment rather than enforcing strict alignment, FLEX-Seg learns robust representations while capturing rich stylistic variations. Experiments across five real-world datasets demonstrate consistent improvements over state-of-the-art methods, achieving 2.44% and 2.63% mIoU gains on ACDC and Dark Zurich. Our findings validate that adaptive strategies for handling imperfect synthetic data lead to superior domain generalization.
Fields of Study & Subjects
Domain Adaptation and Few-Shot Learning
Advanced Neural Network Applications
Medical Image Segmentation Techniques
Publication details
- Journal / source
- Underline Science Inc.
- Publication date
- 7 January 2026
- Language
- EN