DeCode: Decoupling Content and Delivery for Medical QA

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Authors: Po-Jen Ko, Chen-Han Tsai, Yu-Shao Peng
Cited by: 0

Abstract

Large language models (LLMs) exhibit strong medical knowledge and can generate factually accurate responses. However, existing models often fail to account for individual patient contexts, producing answers that are clinically correct yet poorly aligned with patients' needs. In this work, we introduce DeCode (Decoupling Content and Delivery), a training-free, model-agnostic framework that adapts existing LLMs to produce contextualized answers in clinical settings. We evaluate DeCode on OpenAI HealthBench, a comprehensive and challenging benchmark designed to assess clinical relevance and validity of LLM responses. DeCode boosts zero-shot performance from 28.4% to 49.8% and achieves new state-of-the-art compared to existing methods. Experimental results suggest the effectiveness of DeCode in improving clinical question answering of LLMs.

Fields of Study & Subjects

Topic Modeling Machine Learning in Healthcare Artificial Intelligence in Healthcare and Education

Publication details

Journal / source
arXiv (Cornell University)
Publication date
5 January 2026
Document type
Preprint