tilepy: A Flexible Open-Source Scheduling Engine for Time-Domain and Multi-Messenger Astronomy

The era of multi-messenger astrophysics requires rapid and efficient follow-up of transient events, many of which, such as gravitational waves (GW), gamma-ray bursts (GRB), and high-energy neutrinos, suffer from poor sky localisation. We present tilepy, a Python-based software designed to optimize observation schedules for these events. We here detail the modular architecture of tilepy, which separates high-level scheduling logic from low-level tiling and pointing tools, enabling full adaptability for ground- and space-based observatories. Furthermore, we describe the integration of tilepy into the Astro-COLIBRI platform, providing the community with a user-friendly interface and API for triggering complex observation campaigns in real time.