Virtual Theranostic Trials: New Approach Methodologies (NAMs) and Precision Radiopharmaceutical Therapies

arXiv (Cornell University) 2026 Preprint Open access

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Authors: Carlos Uribe, Hamid Abdollahi, Tahir Yusufaly, Taylor J. McColl, Maziar Sabouri, JAMES FOWLER, Fereshteh Yousefirizi, Babak Saboury, Pedro Luis Esquinas, Arman Rahmim
DOI: 10.48550/arxiv.2602.10570
Cited by: 0

Abstract

Radiopharmaceutical therapies are expanding rapidly, but clinical evidence generation is limited by operational constraints and biological heterogeneity in radiopharmaceutical delivery and radiation risk. Virtual theranostic trials can run as companion trials, linking quantitative imaging to patient-specific models to generate evidence for personalized injections and scheduling, accelerate development, and broaden access.

Fields of Study & Subjects

Radiopharmaceutical Chemistry and Applications Medical Imaging Techniques and Applications Artificial Intelligence in Healthcare and Education

Publication details

Journal / source
arXiv (Cornell University)
Publication date
11 February 2026
Language
EN
Document type
Preprint