Safe hypotheses testing with application to order restricted inference

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Authors: Ori Davidov
Cited by: 0

Abstract

Hypothesis tests under order restrictions arise in a wide range of scientific applications. By exploiting inequality constraints, such tests can achieve substantial gains in power and interpretability. However, these gains come at a cost: when the imposed constraints are misspecified, the resulting inferences may be misleading or even invalid, and Type III errors may occur, i.e., the null hypothesis may be rejected when neither the null nor the alternative is true. To address this problem, this paper introduces safe tests. Heuristically, a safe test is a testing procedure that is asymptotically free of Type III errors. The proposed test is accompanied by a certificate of validity, a pre--test that assesses whether the original hypotheses are consistent with the data, thereby ensuring that the null hypothesis is rejected only when warranted, enabling principled inference without risk of systematic error. Although the development in this paper focus on testing problems in order--restricted inference, the underlying ideas are more broadly applicable. The proposed methodology is evaluated through simulation studies and the analysis of well--known illustrative data examples, demonstrating strong protection against Type III errors while maintaining power comparable to standard procedures.

Fields of Study & Subjects

Statistical Methods in Clinical Trials Statistical Methods and Inference Probability and Statistical Research

Publication details

Journal / source
arXiv (Cornell University)
Publication date
17 February 2026
Language
EN
Document type
Preprint