Deciphering the etiology of the 2024 outbreak of undiagnosed febrile illness in Panzi, Democratic Republic of the Congo.

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Authors: Tony Wawina-Bokalanga, Jean-Claude Makangara-Cigolo, Rilia Ola-Mpumbe, Emmanuel Lokilo, François Mwakisenda-Tshakotsho, Delphine Mbonga Mande, Immaculée Kahindo, Alphonse Tshonaka-Nkololo, Emmanuel Hasivirwe Vakaniaki, Nicholas Loman, Sarah Houben, Raphaël Lumembe-Numbi
+35 more Eddy Kinganda-Lusamaki, Ange Ponga-Museme, Yero Mukota-Nungu, Anuj Kumar, Matondo Meris, Samuel Wilkinson, Raquel Colquhoun, Kelly-Michel Kenye, Prince Akil-Bandali, Adrienne Amuri-Aziza, Gustavo Sganzerla Martinez, David J. Kelvin, Ronald Dijkman, Lisa E. Hensley, Cris Kasita, Franck Kafua-Wemba, Dieudonné Mwamba, Lorenzo Subissi, Nicole A. Hoff, Martine Peeters, Anne W. Rimoin, John L. Mokili, Octavie Lunguya-Metila, Edith Nkwembe, Andrew Rambaut, Laurens Liesenborghs, Nicola N Low, Jason Kindrachuk, Koen Vercauteren, Robert Edwards, Jenna Nicole Kelly, Placide Mbala-Kingebeni, Steve Ahuka‐Mundeke, Dieudonné N. Mumba, Jean‐Jacques Muyembé‐Tamfum
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Abstract

In late 2024, an outbreak of over 400 cases of undiagnosed febrile illness, predominantly presenting as fever and cough, was reported in Panzi Health Zone, southwestern Democratic Republic of the Congo. Here we conducted an epidemiological and laboratory investigation to determine the etiology of the outbreak. Clinical data and specimens were prospectively collected from 108 individuals, of whom 59/108 (54.6%) were female. Children aged

Fields of Study & Subjects

Malaria Research and Control Mosquito-borne diseases and control Viral Infections and Outbreaks Research

Publication details

Journal / source
Open Access CRIS of the University of Bern
Publication date
1 April 2026
Language
EN