Comparative Efficacy of 4% Articaine with 1:1,00,000 Epinephrine Buccal Infiltration and 2% Lignocaine with 1:80,000 Epinephrine Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis: A Randomized Clinical Trial
Abstract
The low pKa increases the availability of uncharged base molecules for diffusion through the nerve sheath; as such, onset time is reduced.According to some authors, its ability to diffuse can produce pulpal anesthesia in mandibular teeth after infiltration anesthesia.[7][8][9] Studies have demonstrated that articaine and lignocaine, when administered as a buccal infiltration, can significantly enhance pulpal anesthesia, 1-
Fields of Study & Subjects
Dental Anxiety and Anesthesia Techniques
Anesthesia and Pain Management
Endodontics and Root Canal Treatments
Publication details
- Journal / source
- World Journal of Dentistry
- Volume
- 17
- Issue
- 1
- Pages
- 10–13
- Publication date
- 13 February 2026
- Language
- EN