Evaluation of the Efficacy of Three Remineralizing Agents on Demineralized Enamel after Orthodontic Brackets Debonding: A Comparative Study

Aim:The aim of the current study was to assess the effectiveness of three remineralizing agents on demineralized enamel following the debonding of orthodontic brackets.Materials and methods: Sixty healthy human premolar teeth that were extracted during orthodontic treatment were bonded with brackets and kept in deionized water for a week.Later, they were debonded, and the residual composite was removed with finishing discs and were subjected to pH cycling for 14 days at 37°C to replicate the oral cavity environment.Samples were submerged in a demineralizing solution for 14 days.All 60 teeth were randomly divided into three groups (n = 20)-group I: Application of Toothmin agent, group II: Application of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), and group III: Application of Amflor toothpaste.A scanning electron microscope was used to investigate for the enamel surface demineralization.All data were recorded and statistically analyzed.Results: At baseline, the mean enamel demineralized area was 118.26 ± 0.16 in the Toothmin agent group, 119.08 ± 0.09 in the CPP-ACP agent group, and 117.80 ± 0.10 in the Amflor toothpaste group.The maximum reduction of the demineralized area was found in the CPP-ACP agent group with a mean value of 101.20 ± 0.12 followed by the Toothmin agent group with a mean value of 104.46 ± 0.06 and the Amflor toothpaste group with a mean value of 110.80 ± 0.10.A significant difference was found between the groups.Conclusion: The present study concluded that the CPP-ACP agent group had the greatest reduction in demineralized area when compared to the Toothmin agent group and the Amflor toothpaste group.Clinical significance: After orthodontic treatment, demineralized areas frequently appear on the labial surfaces of teeth.As a result, these lesions present esthetic difficulties, which impact the patient's perception of treatment satisfaction.Because esthetics and appearance are of the highest importance following orthodontic treatment, elimination techniques for remineralization of demineralized regions must be implemented economically.