A Comparative Study of Intrathecal Dexmedetomidine and Fentanyl as Adjuvants to Hyperbaric Bupivacaine in Spinal Anesthesia for Lower Abdominal and Lower Limb Surgeries: A Prospective Randomized Double-blind Clinical Trial
Abstract
Due to its simplicit y and cost-ef fec tiveness, the subarachnoid block is a time tested as well as more reliable technique of regional anesthesia for lower abdominal and lower limb surgeries.Despite widespread use of bupivacaine alone in spinal anesthesia, the short duration of its action often limits its use in prolonged surgeries and for postoperative pain control.[1][2][3] To address these limitations nowadays, many adjuvants such as opioids, magnesium sulphate, vasopressors, and alpha-2 adrenergic agonists (clonidine and dexmedetomidine) have been extensively used.
Fields of Study & Subjects
Anesthesia and Pain Management
Anesthesia and Sedative Agents
Pain Management and Opioid Use
Publication details
- Journal / source
- Journal of Research & Innovation in Anesthesia
- Volume
- 10
- Issue
- 2
- Pages
- 45–55
- Publication date
- 5 February 2026
- Language
- EN