Substrate-dependent Differences of Colonic Hydrogen Production in a Patient With Fructose Malabsorption
Abstract
BACKGROUNDHydrogen (H 2 )/methane (CH 4 ) breath testing (HMBT) is the most widely utilized diagnostic modality for the diagnosis of many common gastrointestinal conditions including small intestinal bacterial overgrowth (SIBO), intestinal methanogen overgrowth (IMO), irritable bowel syndrome-like symptoms, and carbohydrate malabsorption.[1][2][3] Often, in interpreting the lactulose HMBT, the term "hydrogen nonproducer" is used for a H 2 breath profile that is "flatline".4,5 Here we report on a patient with abnormal fructose HMBT results that failed to produce H 2 upon lactulose, glucose, lactose, and sorbitol HMBT. Substrate-dependent Differences of Colonic Hydrogen Production in a Patient With Fructose Malabsorption
Fields of Study & Subjects
Hydrogen's biological and therapeutic effects
Gastrointestinal motility and disorders
Advanced Chemical Sensor Technologies
Publication details
- Journal / source
- Journal of Neurogastroenterology and Motility
- Publisher
- The Korean Society of Neurogastroenterology and Motility
- Volume
- 32
- Issue
- 2
- Pages
- 300–301
- Publication date
- 9 February 2026
- Language
- EN