Interstitial Cells of Cajal Remodeling as a Mechanistic Insight Into the Natural History of Achalasia: Lessons From 3 Clinical Cases

Journal of Neurogastroenterology and Motility 2026 Open access

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Authors: Ziwei Li, Youhong Hu, Bibo Zhong, Jiguang Kou, Anlong Yuan
DOI: 10.5056/jnm25182
Cited by: 0

Abstract

We read with great interest recent casebased report in Journal of Neurogastroenterology and Motility describing the dynamic clinical course of achalasia.Taken together from another reports, these cases illustrate not only the progression of esophageal motor dysfunction but also the potential for partial remission, providing a unique window to consider the role of interstitial cells of Cajal (ICC) remodeling in disease evolution.

Fields of Study & Subjects

Gastroesophageal reflux and treatments Gastrointestinal motility and disorders Neuroscience of respiration and sleep

Publication details

Journal / source
Journal of Neurogastroenterology and Motility
Volume
32
Issue
1
Pages
139–140
Publication date
6 January 2026
Language
EN