Data from: Organ-specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

This dataset supports the manuscript “Organ-specific redox imbalance in spinal muscular atrophy mice and partial rescue by SMN antisense oligonucleotides” submitted to FEBS Letters. It contains raw and processed experimental data generated to investigate tissue-specific redox alterations and lipid peroxidation in a spinal muscular atrophy (SMA) mouse model and following treatment with SMN antisense oligonucleotides. The dataset includes uncropped raw Western blot images corresponding to all main and supplementary figures, quantitative values used for graphical representation and statistical analysis, and raw and processed lipid peroxidation (MDA/TBARS) measurements obtained using a TECAN plate reader. Processed data include blank correction, standard-curve-based conversion to MDA equivalents, normalization to protein content, dilution correction, and final normalization as used for figure generation in GraphPad Prism. All files are organized by figure and assay type, with detailed README documentation and processing notes provided to enable full reproducibility and reuse. This dataset may be reused for independent reanalysis, methodological comparison, or meta-analyses of redox regulation and oxidative stress in neuromuscular disease models.