Data from: Ovarian hormone deficiency enhances wood smoke-induced immune dysfunction via transcriptomic and metabolic alterations

The data were generated from bone marrow immune cells of ovariectomized (OVX) C57BL/6 mice exposed to either filtered air (FA) or wood smoke (WS) to investigate how ovarian hormone deficiency modifies the immunotoxic effects of acute air pollution exposure. The dataset includes raw paired-end FASTQ files and filtered feature-barcode count matrices (.h5 format) for three biological replicates from each of the two experimental groups (OVX-FA and OVX-WS). Please note that other data presented in the manuscript, such as the ex vivo functional and metabolic assays on bone marrow-derived macrophages (BMDMs), are not included in this deposit. These data can be used to reproduce the transcriptomic analyses of bone marrow immune composition, cell-type-specific differential gene expression, and pathway enrichment results described in the manuscript.