Data from: Photodynamic therapy with infracyanine green induces keratocyte depopulation in the normal equine cornea

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Authors: Callie M. Rogers, Eric C. Ledbetter, Abigail M. Reid, Erin Scott, Kelly E. Knickelbein
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Abstract

The purpose of this study was to investigate the morphologic effects and safety of in vivo photodynamic therapy (PDT) on the healthy equine cornea. Six university-owned horses underwent unilateral corneal PDT with intrastromal infracyanine green and photoactivation with an 810nm diode laser (500mW for 2.5 min = 75 Joules). Complete ophthalmic examinations, clinical scoring, digital and infrared photography, ocular thermography, in vivo confocal microscopy (IVCM), and ultrasound biomicroscopy (UBM) were performed pre-treatment and post-treatment on study days 1, 5, 15, 33, and 103.

Fields of Study & Subjects

Photodynamic Therapy Research Studies Corneal surgery and disorders Ocular Infections and Treatments

Publication details

Journal / source
DRYAD
Publication date
27 February 2026
Language
EN
Document type
Dataset