A study of cases of transoral resection for pharyngeal or laryngeal cancer

Objective : The purpose of this study was to examine factors associated with local recurrence and neck metastasis in transoral endoscopic surgery.Patients and Methods : Ninety-two lesions in 87 cases of transoral surgery for malignant pharyngeal or laryngeal tumors were included in the study.The following items were examined : occasion of discovery, other multiple cancers, treatment details, relationship between final pathology recurrence/metastasis, and treatment outcomes.Results : 59.8％ of cases were detected during upper gastrointestinal endoscopy.Metachronous multiple primary cancers were observed in 78.2％.Tracheostomy was performed concurrently in 9.4％, and postoperative dysphagia occurred in 5.7％.The negative margin rate in permanent pathology was 75.0％.Local recurrence occurred in 7.8％, and distant metastasis was present in 4.8％ of cN0 cases.Summary : In transoral endoscopic surgery for pharyngeal or laryngeal carcinoma, the local recurrence rate was higher in cases with positive margins/close margins and prior radiation therapy.The neck metastasis rate was higher in cases with cT2 or higher tumor stage, positive margins/close margins, and tumor thickness of 1 mm or greater.