Pulmonary granular cell tumor coexisting with interstitial lung disease – a rare case report

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Authors: Zeynep Sagnak Yilmaz, Şafak Ersöz, Elif Özsağır, Kubra Turker, Olcay Ayçiçek, Deha Çebi Öztürk
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Abstract

A granular cell tumor (GCT) is a soft tissue neoplasm of rare occurrence in the lung. A 44-year-old male asphalt worker had interstitial lung disease. Incidentally, a 7 mm polypoid nodule was observed at the entrance of the right upper lobe bronchus. Tumor cells were characterized by a large granular eosinophilic cytoplasm and small, uniform nuclei. The neoplastic cells were diffuse positive for S-100, CD-68, NSE, vimentin, and SOX-10, and focal positive for calretinin and inhibin A. This case is unique in its distinction as the second literature case of pulmonary GCT coexisting with interstitial lung disease.

Fields of Study & Subjects

Tumors and Oncological Cases Medical Imaging and Pathology Studies Sarcoidosis and Beryllium Toxicity Research

Publication details

Journal / source
Polish Journal of Pathology
Volume
76
Issue
4
Pages
338–342
Publication date
19 January 2026
Language
EN