Evaluation of The Toxic Effects of Some Male Sexual Enhancement Drugs in the Testes of Male Wistar Rats

Journal of Science Technology and Innovation Research 2026 Open access

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Authors: Basirat Adedamola Salami, Opeoluwa Ogundimu, Victor Sasaenia Adedoyin, Bukola Adeyemi-Ekeolu, Omolara Adeola Olaleye, Emeka Taye Umezurike, Kehinde Adegbehingbe, Kehinde Mary Akinde
DOI: 10.51459/jostir.2025.1.special-issue.0233
Cited by: 0
References: 18

Abstract

Testicular damage is one of the most commonly reported adverse effect associated with many herbal drugs in Nigeria. This study evaluated the toxic effects of some male sexual enhancement drugs (ST and DB) in the testis of male Wistar rats. 18 male Wistar rats were randomized into three groups of 6 each. Group I received distilled water only, while others were administered 10 mL/Kg of ST and DB for 14 days respectively. Thereafter, the rats were sacrificed, the testes were harvested and testicular antioxidant concentration was evaluated. Rats treated with ST and DB had significantly (p

Fields of Study & Subjects

Sperm and Testicular Function Pharmaceutical Quality and Counterfeiting Hormonal and reproductive studies

Publication details

Journal / source
Journal of Science Technology and Innovation Research
Volume
1
Issue
Special-Issue
Publication date
27 February 2026
Language
EN