Diagnosis of Kidney Diseases: A Spotlight on Genetic Testing

Kidney diseases are a significant burden on public health, necessitating improved diagnostic strategies for timely interven tion and management. Genetic testing has emerged as a promising approach to enhance the diagnosis of different diseases by uncovering underlying genetic factors. Genetic testing offers numerous advantages in the diagnosis of kidney diseases, including the identification of specific genetic variants associated with various kidney conditions. With a high burden of kid ney diseases in developing countries, genetic testing holds immense promise in providing accurate and timely diagnoses and managing these conditions. This approach enables clinicians to determine the genetic basis of kidney diseases, facili tating personalized treatment plans and family counseling. This article highlights the availability and accessibility of kidney genetic testing facilities, exploring the advancements made in this field. It also addresses the unique challenges faced by the developing countries’ population, such as genetic heterogeneity and diverse ethnic backgrounds, which necessitate tailored approaches for genetic testing. It addresses the ethical considerations surrounding genetic testing and the impor tance of informed consent and genetic counseling services. In conclusion, this article emphasizes the growing significance of genetic testing in the diagnosis of kidney diseases, emphasizing its potential to revolutionize patient care and improve outcomes and the need for further research and collaborative efforts to establish standardized guidelines and protocols. Cite this article as: Devi C, Das P. Diagnosis of kidney diseases: A spotlight on genetic testing. Turk J Nephrol. 2026;35(1):4-14.