Bèta-thalassemie: een verrassend radiologisch beeld
Abstract
The aetiology of thalassaemia lies in a defect in the synthesis of 1 of the 2 chains, alpha or beta, of the haemoglobin molecule. This failure primarily results in haemolytic anaemia, which is the main clinical feature of the disorder. As a consequence of this haemolysis, erythropoiesis is stimulated, which in turn leads to morphological changes in the bone and hypertrophy of other organs. Radiographic findings reveal a decrease in cortical thickness accompanied by trabecular reduction in the bone, including the facial bones. Commonly, no local treatment is required in the field of maxillofacial or dental care.
Fields of Study & Subjects
Hemoglobinopathies and Related Disorders
Clinical Laboratory Practices and Quality Control
Pharmacological Effects and Toxicity Studies
Publication details
- Journal / source
- Nederlands Tijdschrift voor Tandheelkunde
- Volume
- 133
- Issue
- 01
- Pages
- 9–11
- Publication date
- 5 January 2026
- Language
- NL