Excimer laser coronary angioplasty in coronary chronic total occlusion: a comparative analysis with OCT navigation

Emergency Cardiology and Cardiovascular Risks 2026 Open access

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Authors: M. A. Klimau, A. S. Pastayalka, С. А. Сивак, S. A. Pastayalka
DOI: 10.51922/2616-633x.2025.9.2.2604
Cited by: 0
References: 24

Abstract

Aim: To compare the safety and efficacy of excimer laser coronary angioplasty (ELCA) versus conventional CTO-PCI under routine OCT guidance and speckle-tracking echocardiography. Materials and methods: a single-center cohort study included 36 ELCA patients and 22 controls without laser. The endpoints included technical success, OCT parameters (MSA, apposition), changes in GLS and LVEF, and a 12-month MACE. Results: ELCA yielded a larger stent area, a lower malapposition, and greater improvements in GLS and LVEF with comparable safety. Conclusion: OCT-guided ELCA improves stent geometry and LV functional recovery compared with non-laser CTO-PCI.

Fields of Study & Subjects

Coronary Interventions and Diagnostics Cardiac Imaging and Diagnostics Acute Myocardial Infarction Research

Publication details

Journal / source
Emergency Cardiology and Cardiovascular Risks
Volume
9
Issue
2
Pages
2604–2610
Publication date
25 January 2026