Synovial fluid α -defensin might be false positive in early stages after major total arthroplasty revision surgery

Journal of Bone and Joint Infection 2026 Open access

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Authors: Sankalp Mrutyunjaya, Wade A. Banta, Joseph Raymund Espiritu, Derek F. Amanatullah
DOI: 10.5194/jbji-11-1-2026
Cited by: 0
References: 14

Abstract

Generalizability is critical when evaluating the performance of a diagnostic test to ensure variations in the patient population are represented. We report a case of a patient receiving multiple false positive results from the synovial α -defensin test observed over close to a 3-year period following revision total knee arthroplasty.

Fields of Study & Subjects

Antimicrobial Peptides and Activities Osteoarthritis Treatment and Mechanisms Orthopedic Infections and Treatments

Publication details

Journal / source
Journal of Bone and Joint Infection
Volume
11
Issue
1
Pages
1–4
Publication date
7 January 2026
Language
EN