TISSUE RESPIRATION AS A CENTRAL LINK IN ENERGY METABOLISM: PHYSIOLOGICAL MECHANISMS AND REGULATION

Tissue respiration is a dynamic system whose function is to ensure the adaptation of energy metabolism to the changing needs of cells and, accordingly, the organism and combines molecular mechanisms in mitochondria with the physiological needs of tissues.Its regulation is tissue-specific and includes such processes as the control of oxidative phosphorylation, membrane proton permeability and signaling effects of reactive oxygen species, especially under conditions of hypoxia.It is important to note that the intensity of cellular respiration is influenced by various external factors, such as environmental conditions, physical activity, behavioral characteristics, and in skeletal muscles the respiratory capacity of mitochondria determines the limits of endurance and adaptation to loads.The purpose of the study: to evaluate and systematize modern data on the physiological mechanisms and regulation of tissue respiration.Materials and methods: a review of sources in the Журнал «Перспективи та інновації науки» № 2(60) 2026