REMODELING OF STRUCTURAL COMPONENTS OF THE DISTAL SMALL INTESTINE FOLLOWING BLAST-INDUCED INJURY

At present, blast-related injuries of the abdominal organs, including the small intestine, remain a significant medical and social problem.Despite a substantial number of studies addressing the systemic manifestations of blast injury, the microscopic morphological features of the distal small intestine remain insufficiently investigated.Therefore, the aim of this study was to evaluate histological changes in the structural components of the ileal wall under conditions of blast-induced injury.The study was conducted on 20 sexually mature rats divided into a control group (animal fixation without exposure to an exogenous factor) and experimental groups with simulated abdominal blast-induced injury.Animals were euthanized 1 hour, 7 days, and 14 days after exposure.Macroscopic and microscopic changes in the distal small intestine were assessed.Morphological analysis of histological specimens was