Étude Ethnobotanique Et Phytochimique Des Plantes Médicinales Utilisées Contre Le Paludisme Dans Le Territoire De Kasangulu Cas De Villages Kingatoko Et Mingadi (Province Du Kongo Central) En République Démocratique Du Congo

Objective: This work values endogenous knowledge on medicinal plants used against malaria in the villages of Kingatoko and Mingadi (DRC), while determining their chemical constituents.Ethnobotanical Methodology and ResultsAn oral questionnaire was administered to the informants. Taxonomic analysis revealed 12 species from 11 genera and 11 families, dominated by Rubiaceae, which are rich in pharmacodynamic secondary metabolites. Decoction of the leaves was the predominant method of preparation and oral administration. Morinda morindoides and Morinda lucida had the highest citation frequencies, with usage agreement values >0.10 for Morinda morindoides, Morinda lucida, Moringa oleifera, and Rauvolfia vomitoria. Similar usage patterns were observed between villages. Phytochemical screening: Qualitative screening of these four species showed the presence of alkaloids and tannins in all phases (aqueous and ethanolic), polyphenols in both phases except the ethanolic phase of Morinda lucida, anthocyanins and quinones predominantly in the aqueous phase, and flavonoids in the aqueous phase for three species. Saponins were absent.Conclusion and outlookThis study enriches knowledge about natural resources, guides the production of improved traditional medicines against malaria, and prioritizes conservation in the face of overexploitation.