Peer Review Report For: The Effect of Coconut and Frankincense Oils on the Biofilm Growth of Streptococcus mutans [version 1; peer review: 2 approved, 1 approved with reservations]

Background This study aimed to investigate the antibiofilm effect of coconut and frankincense oils. Methods Different types of coconut (organic refined, cocos nucifera, organic virgin, and organic extra virgin) and frankincense (frankincense pure essential oil in fractionated coconut oil and uplifting frankincense pure essential) oils were investigated. Serial dilutions (1:3, 1:6, 1:12, 1:24, 1:48, 1:96, and 1:192) were created from each oil and incubated with an overnight culture of S. mutans. The total growth and biofilms absorbance were measured at 595 and 490 nm, respectively. One-way ANOVA and Tukey tests were used for data analysis. Results The greatest biofilm inhibition was observed in the uplifting frankincense pure essential oil at 1:3 dilution (0.67±0.12), which was significantly lower ( p