Comprasion of the quality of life of patients who have undergone reconstructive and plastic surgery after mastectomy

Breast cancer (BC) is one of the most prevalent forms of malignant neoplasm among the female population, both within the Russian Federation and globally. Given that the primary treatment modality for this oncological condition is surgical, entailing the excision of the affected organ, there is an imperative for subsequent reconstruction. Purpose of the study: to make a comparison of data from global studies on the quality of life of patients who underwent non-flap breast reconstruction after mastectomy, based on the Breast-Q and HADS questionnaires. The present literature search was conducted in the PubMed, eLibrary, and Cyberleninka databases for the period from 2016 to 2025. The following keywords were utilised for the search: The following terms are to be considered: “quality of life” “breast reconstruction”, “breast implant”, “mesh implant”, “Breast-Q”, and “HADS”. A comprehensive analysis encompassing original studies, meta-analyses, randomised controlled trials and systematic reviews was conducted. The influence of various factors on patient satisfaction with the appearance of reconstructed breasts and quality of life in terms of physical, psychosocial, and sexual well-being, as well as on the level of anxiety and depression in the postoperative period, was studied. The present study has demonstrated that immediate prepectoral breast reconstruction is associated with higher quality of life (QoL) scores and lower anxiety and depression indices. A decrease in QoL scores has been demonstrated to be associated with the occurrence of complications in the postoperative period. Further research is required to ascertain the extent to which radiation therapy, the type of endoprosthesis, and its additional coverage with a mesh implant impact quality of life indicators.