Putative Roles of Ocimum Gratismum in Paraquat-Altered Motor and Cognitive Behaviors of Male Wistar Rats
Abstract
Neurodegenerative diseases (NDs) are due to progressive loss of neurons, leading to a decline in motor and cognitive functions, memory, and learning. This study investigated the role of Ocimum gratissimum (Og) in paraquat-altered motor and cognitive abilities. 35 Wistar rats were assigned to five groups of 7 rats after 14 days of acclimatization. Group A was the control, Groups B, C, D, and E were exposed to 12 mg/kg of Paraquat (PQ) for 14 days; thereafter, Groups C, D, and E were treated with 200, 400, and 600 mg/kg, respectively. All administrations were oral, and the treatment with Og lasted 14 days. There was a reduced number of lines crossed in Group B and a significant increase in lines in Groups C and D (p
Fields of Study & Subjects
Paraquat toxicity studies and treatments
Phytochemicals and Medicinal Plants
Pesticide Exposure and Toxicity
Publication details
- Journal / source
- International Journal of Public Health and Pharmacology
- Volume
- 6
- Issue
- 1
- Pages
- 76–76
- Publication date
- 12 March 2026
- Language
- EN