Role of Amphiregulin Growth Factor, Progesterone Hormone with Prostaglandin on Successful Implantation in PCOS Women Undergoing ICSI

The growth and maturation of the follicles and oocytes are influenced by many reproductive hormones and growth factors which in turn interfere with the success of fertilization and conception. We assessed the serum and follicular fluid levels of Progesterone, Prostaglandin E2 hormones, and Amphiregulin Growth factor on the day of ova pick-up and embryo transfer using enzyme-linked immunosorbent assay (ELISA). The result showed highly significant differences were encountered between PCOS and non-PCOS groups, serum (P4, PGE2, AREG) on the day of ova pickup (OPU), follicular (P4, PGE2, AREG) on the day of ova pickup (OPU) and embryo transfer (ET), All these variables were significantly (P