Phytosome and Nanophytomedicine: A Brief Overview of Bridging Botanical Power with Nanotechnology

Phytosomes improve the solubility, bioavailability, and therapeutic efficiency of plant extracts, making them a unique delivery method. The chemical interaction of phospholipids and standardized plant extracts results in these phyto-phospholipid complexes, which improve absorption and facilitate better integration into cellular membranes. In the larger and quickly developing discipline of nanophytomedicine, nanoscale technologies are used to maximize the stability, effectiveness, and transport of phytochemicals. The foundations of phytosome technology, such as its composition, methods of synthesis, methods of characterisation, and benefits over conventional herbal formulations and other nanocarriers like liposomes, are the main topic of this review study. With commercially accessible examples like Meriva® (curcumin phytosome) and Siliphos® (silybin phytosome), it also describes the numerous therapeutic uses of phytosomes in hepatoprotection, antioxidant therapy, and inflammation. The integration of phytosomes into contemporary nanophytomedicine systems is also covered in the study, along with upcoming difficulties with scale-up, regulatory approvals, and clinical translation. Phytosomes, a biocompatible and effective delivery system, have great promise to bridge the gap between modern pharmaceutical technology and traditional herbal therapy, promoting the creation of safer, more potent plant-based medicines.