Predicting epistasis across proteins by structural logic
Abstract
We provide the Docker Image to run IntraMutateX, the ML algorithm for predicting intragenic complementation in human ASL as described in our manuscript, “Predicting epistasis across proteins by structural logic." This Docker Image is tested only in CUDA-enabled machine. Please see the README for instructions to load and run the software. Output of the ML algorithm is included as supplemental datasets in the manuscript as well as provided in ASL_ML_plots.zip here. This software and the underlying data are available for academic use under a limited license. For commercial licensing of the data and/or the software, please contact Aimee Dudley and Amarda Shehu.
Fields of Study & Subjects
Genomics and Rare Diseases
Protein Structure and Dynamics
Computational Drug Discovery Methods
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 12 January 2026