Eficacia terapéutica del plasma rico en plaquetas periuretral en mujeres con incontinencia urinaria de esfuerzo

Stress urinary incontinence (SUI) is defined as the involuntary loss of urine that occurs when physical activity exerts pressure on the bladder, leading to urine leakage. This condition affects millions of women worldwide. In this quasi-experimental study, the therapeutic efficacy of periurethral platelet-rich plasma (PRP) injection was evaluated before and after treatment in 25 women with SUI who attended a private gynecology practice. Clinical data were obtained from medical records, urodynamic studies, and the application of the International Consultation Questionnaire Short Form (ICIQ-SF). To assess the severity of SUI, each participant completed a self-evaluation using a 10-point visual analog scale (VAS). A six-step protocol was developed for the periurethral PRP administration. The mean age of the patients was 56.88 ± 9.78 years, and SUI onset occurred between the ages of 43 and 55. Nearly 50% of participants reported that SUI prevented them from performing certain daily activities. Analysis of initial and post-treatment VAS scores revealed statistically significant differences (p < 0.05) in six out of ten evaluated situations following periurethral PRP therapy. Furthermore, 60% of patients with SUI symptoms showed 95% improvement four weeks after treatment. Most women expressed satisfaction with the results and stated they would recommend the procedure. In conclusion, PRP therapy may represent a safe and effective alternative treatment modality to increase urethral resistance and improve female SUI.