Next-generation file format specification

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Authors: Moore, Josh, Bogovic, John, Soltwedel, Johannes, Marconato, Luca, Bennett, Davis, Moore, William, McCormick, Matt, Toloudis, Daniel, Collman, Forrest, Gaudreault, Nathalie, Feng, David, Burel, Jean-Marie
+47 more Swedlow, Jason R., Gold, Ilan, Maitin-Shepard, Jeremy, Stansby, David, Besson, Sébastien, Rzepka, Norman, Perlman, Eric, Lüthi, Joel, Cerrone, Lorenzo, Tischer, Christian, Hartley, Matthew, Albert, Marvin, Allan, Chris, Barnes, Chris, Best, Benedikt T., Boussot, Valentin, Comparin, Tommaso, Deakin, Lachlan, Diabira, Assa, Dunster, Gideon, Eglinger, Jan, Gay, Guillaume, Gui, Xiao, Gunalan, Kabilar, Halchenko, Yaroslav O., Hniopek, Julian, Innerberger, Michael, Kittisopikul, Mark, Lambert, Talley, Linkert, Melissa, Liu, Ziwen, Lubiana, Tiago, Nunez-Iglesias, Juan, Özdemir, Bugra, Palla, Giovanni, Pape, Constantin, Rhode, Sebastian, Scarlett, Virginia, Shepherd, Doug, Uhlmann, Virginie, Vierdag, Wouter-Michiel, Virshup, Isaac, Watson, Alan, Windhager, Jonas, Yamauchi, Kevin, Zubov, Yurii, Zukić, Dženan
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Abstract

A growing community is constructing a next-generation file format (NGFF) for bioimaging to overcome problems of scalability and heterogeneity. Organized by the Open Microscopy Environment (OME), individuals and institutes across diverse modalities facing these problems have designed a format specification process (OME-NGFF) to address these needs. Those community members have built the format itself – OME-Zarr – along with tools and data resources available today to increase FAIR access and remove barriers in the scientific process. The current momentum offers an opportunity to unify a key component of the bioimaging domain — the file format that underlies so many personal, institutional, and global data management and analysis tasks.

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
14 September 2026