The HLH-Risk-Calculator – Reproducible model code & artifacts

The HLH-Risk-Calculator is a machine learning-based software package for predicting initial disease severity and time-point specific mortality in adult patients with secondary haemophagocytic lymphohistiocytosis (HLH). This Zenodo record provides a permanent, citable archive of the software version used in the study by Ruzicka M et al., accepted for publication in Intensive Care Medicine (2026). The archived release includes source code, trained model artifacts, environment specifications, and methodological documentation required for computational reproducibility. Clinical patient-level data are not included because of data protection and privacy regulations. The associated GitHub repository provides the actively maintained version of the software.